Synthesis structure and properties of carbohydrates and glycoconjugates
Synthesis and structural properties of polysaccharides and glycoconjugates, with particular attention to the components of the outer membrane and capsule of pathogenic, extremophile and symbiotic bacteria. New protocols in glycochemistry. Synthesis and modification of mono-, oligo- and poly-saccharides and glycoconjugates with potential immune-modulatory activity, as vaccines or as molecular carriers. Study of the interactions between host and bacteria or external environment and bacteria. Total enantio- and diastereo-selective syntheses and domino procedures for the production of non-natural carbohydrates. Synthesis of glycomimetics with inhibitory and chaperone activity or as artificial ionophores. Analysis of the glycidic portion of viral glycoproteins. Use of natural or chemically modified carbohydrates in tanning technique.