Premio "Miglior Poster 2019" della SCI Divisione Inorganica
Alfonso Annunziata awarded for the best poster presentation.
Alfonso Annunziata: PhD student in Chemical Sciences
Alfonso has been awarded for the best poster presentation at the XLVII National Meeting of Inorganic Chemistry of Italian Chemical Society.
Title: Glycoconjugate carbene Pt(IV) complexes: synthesis, characterization and cytotoxic activity
Summary of the research: Platinum compounds have been widely used in chemotherapeutic treatments for about 40 years. Despite their success, they often involve the insurgence of dramatic side effects and drug resistance which reduce the efficacy of the therapy. The Group of Organometallic Chemistry (METOR Group) at the Department of Chemical Sciences is widely focused on the research of new potential anticancer agents following the strategy of glycoconjugation, a stated alternative to reduce the collateral effects of Pt-based therapy. Currently, promising results have been obtained in the study of molecules that have shown better performances compared with the common platinum-based drugs.
The PhD course in Chemical Sciences is conceived at providing advanced and rigorous training to the next scientists generation, featuring innovative and independent skills in the organization and management of research and development activities, in Academia and Industry, in several chemical sectors.
Great attention is devoted to multidisciplinary aspects of research and its integration with related disciplines (such as Physics, Biology, Engineering), in order to broaden the knowledge horizon and, therefore, future job opportunities. The training includes different orientations that while sharing the scientific and methodological approach, are aimed at understanding structure/function/properties relationships in compounds and materials of different nature and simultaneously at identifying possible applications in cutting-edge sectors, ranging from catalysis, sensors, micro- and opto-electronics, biomedicine, biology and diagnostics.
The teaching and research activity is namely focused on the following topics:
- chemistry and biochemistry of peptides, proteins and nucleic acids;
- inorganic and bioinorganic chemistry, for the development of metallorganic complexes and synthetic metalloproteins;
- chemistry and physics of polymeric and nanostructured materials;
- reactivity and catalysis in industrial and biotechnological processes;
- synthesis, structure, reaction mechanisms and bioactivity of organic molecules;
- development of analytical methodologies of interest in the areas of environment, food safety and cultural heritage;
- development of theoretical and computational models and methods.
For more details, it is suggested to browse the research section of the Department website (link).
The PhD School in Chemical Sciences, to commemorate Giulio Regeni, his sacrifice and commitment for freedom in scientic research, dedicates to him one scholarship for each PhD cycle.
The PhD course has a strong international imprinting, as a multiplicity of collaborative relationships with prestigious foreign institutions are cultivated (link).
Thanks to a collaboration between the "An-Najah National University", Nablus, Palestine and the University of Napoli "Federico II" in the field of higher education and scientific research, since 2016, the PhD in Chemical Sciences offers for each cycle a position for graduate students from An-Najah University.
Prof. Angelina Lombardi (coordinator)
Dott. Annarita Quartuccio (secretary)